Case study · Top-5 pharma · Clinical trials

AI-driven pre-screening for intermediate AMD

Historic pre-screen failure of roughly 60%. Eligibility signals sat in unstructured notes and imaging that no manual chart review could cover at scale.

04 · Top-5 pharma · Clinical trials

A two-phase read: records, then imaging

A two-phase pipeline reads real-world ophthalmic records to find eligible patients for an intermediate-AMD study — de-identified, on secure infrastructure, source data resident with the site.

Phase 1 · records Phase 2 · OCT
The bottleneck

Historic pre-screen failure of roughly 60%. Eligibility signals sat in unstructured notes and imaging that no manual chart review could cover at scale.

What we built
  • Phase 1 — generative AI reads de-identified records against inclusion and exclusion criteria
  • Phase 2 — OCT image segmentation refines the shortlist against imaging criteria
  • Every flagged patient carries the evidence that triggered the flag
  • Deployed against data from a leading European academic eye centre
Targets

Two times the historical screen rate and pre-screen failure below 50%, per the research plan. GDPR-compliant throughout, with source data never leaving the site.

Now reusable

deidentify · cohort_matching · image_segmentation — a pre-screening pattern extensible to other indications and modalities.

This is the deployment behind the Clinical trials page — the same de-identify, cohort-match, and image-segmentation pattern, extensible to other indications and imaging modalities.

See the Clinical trials solution →

See the other three deployments.

Client names, references, and full results available under NDA.

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